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Twist Bioscience and Element Biosciences Expand Collaboration to Advance Trinity-Enabled Sequencing Workflows

26 May 2025
Admin
News Article

Twist Bioscience and Element Biosciences Expand Collaboration to Advance Trinity-Enabled Sequencing Workflows

Twist Bioscience Corporation (NASDAQ: TWST), a leader in synthetic DNA solutions, and Element Biosciences, Inc., a company dedicated to democratizing access to advanced life sciences tools, today announced the expansion of their strategic collaboration.

This partnership aims to enhance Element’s AVITI™ systems and Trinity flowcells with new Twist library preparation and target enrichment workflows—further streamlining next-generation sequencing (NGS) applications from library prep through sequencing.

Twist Gains Exclusive Access to Trinity-Compatible NGS Workflow Development

Twist will gain exclusive rights to develop additional library preparation and target enrichment workflows compatible with Element’s Trinity sequencing technology. This builds upon the successful launch of:

Twist's Element-native kit
The 1-hour fast hybridization Trinity solution

“This collaboration builds on our existing relationship with Element... giving customers access to the uniformity, consistency and quality provided by our NGS tools,”

— Emily M. Leproust, CEO and Co-founder, Twist Bioscience

Key Benefits of the Expanded Collaboration:

Rapidly streamline hybrid capture processes, both off and on the sequencer
Enable broader adoption across markets including:
- Agricultural biotechnology (AgBio)
- Population genomics
- Clinical research
Offer customers platform flexibility without compromising performance
Demonstrate the versatility of Twist’s NGS products across sequencing platforms

Empowering End-to-End Sequencing on the AVITI Platform

This expanded partnership will enable researchers to access full end-to-end workflows, including:

Library preparation
Target enrichment
Sequencing using Element’s AVITI platform, known for:
- High-quality sequencing output
- Flexible and scalable performance

Twist and Element will also collaborate on joint commercial and promotional activities to enhance customer awareness and adoption.

“By uniting our revolutionary Trinity workflow with Twist's superior library prep capabilities, we’re creating an integrated solution that catalyzes access to premium life science tools,”

— Molly He, CEO and Co-founder, Element Biosciences

Expanding Beyond Exome: Trinity Workflows for More NGS Applications

The partnership aims to expand Trinity workflows beyond exome sequencing to other critical NGS applications. Twist’s NGS solutions are designed to be:

Broadly compatible
Highly uniform and consistent
Ideal for both research and clinical-grade sequencing applications

About Twist Bioscience Corporation

At Twist Bioscience, the mission is to empower customers who are improving lives and solving global challenges through innovation in:

Medicine
Agriculture
Industrial chemicals
Defense and synthetic biology

Unique Platform Advantage:

Twist leverages a proprietary silicon-based DNA synthesis platform, which enables:

High-throughput, cost-effective synthesis
Precision and speed at scale
Rapid product development across DNA synthesis, sequencing, and therapeutic discovery