Spero Therapeutics, Inc., A Multi-Asset Clinical-Stage Biopharmaceutical Company, Focused On Identifying, Developing And Commercializing Treatments In High Unmet Need Areas Involving Rare Diseases And Multi-Drug Resistant (Mdr) Bacterial Infections, Today Announced The Closing Of Its Previously Announced Exclusive License Agreement With Glaxosmithkline Intellectual Property (No. 3) Limited For Tebipenem Hbr, An Investigational Drug Being Developed As The Potentially First Oral Carbapenem Antibiotic For The Treatment Of Complicated Urinary Tract Infections (Cuti), Including Pyelonephritis, Caused By Certain Bacteria.Pursuant To The License Agreement, Spero Will Be Receiving A $66 Million Upfront Payment From Gsk And Is Eligible To Receive Up To $525 Million In Development, Sales, And Commercial Milestones Payments, As Well As Low-Single Digit To Low-Double Digit Tiered Royalties On Net Product Sales. In Exchange, Gsk Has Been Granted An Exclusive License To Develop And Commercialize Tebipenem Pivoxil And Tebipenem Pivoxil Hbr In All Territories, Except Japan, And Certain Other Asian Countries, Territories Which Will Be Retained By Spero Partner, Meiji Seika. In Connection With Closing, Pursuant To The License Agreement And A Previously Announced Stock Purchase Agreement Between The Parties, An Affiliate Of Gsk Has Purchased 7,450,000 Shares Of Spero
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