Sciwind Biosciences begins patient dosing in phase 3 trials of ecnoglutide to treat type 2 diabetes in China
Sciwind Biosciences Co., Ltd., a clinical-stage biopharmaceutical company, announced the initiation of patient dosing in phase 3 clinical trials of ecnoglutide (XW003) in adult patients with type 2 diabetes in China. Ecnoglutide is a novel, long-acting glucagon-like peptide-1 (GLP-1) analog optimized for improved biological activity, cost-effective manufacturing, and once-weekly dosing. It was shown to be safe and well tolerated, as well as to result in robust HbA1c and weight reductions in phase 2 clinical trials.
The first phase 3 trial (NCT05680155) of the pivotal study is a multicenter, double-blind, randomized, placebo-controlled trial to evaluate the efficacy and safety of once-weekly subcutaneous administration of ecnoglutide in approximately 210 treatment-na
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