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25 Jun 2021
Admin
News Article

ProBioGen LAVA Enter Agreement For Cell Line Development For Manufacturing Of Novel Bispecific

ProBioGen and LAVA Therapeutics N.V. announced the closing of a second cell line development agreement to support a bispecific gamma-delta T cell engager (TCE) candidate in LAVA's pipeline.Under the agreement and using its CHO.RiGH expression platform, including its DirectedLuck Transposase technology for the generation of stable high-titer cell lines, ProBioGen will conduct cell line development of a novel gamma-delta bsTCE."We are delighted to continue our collaboration with LAVA to develop cell lines for another novel gamma-delta bsTCE. Our proven cell line development platform, which also includes our Transposase technology, is perfectly suited for novel protein formats", said ProBioGen's chief executive officer Dr. Lutz Hilbrich."Based on the great results from our previous agreement, we would look forward working with ProBioGen again", commented Stephen Hurly, chief executive officer and president of LAVA Therapeutics. "ProBioGen exceeded our expectations and proved to be a scientifically driven partner with a proven development platform and a dedicated analytical panel for bispecific antibody formats."ProBioGen is a specialist in the development and manufacturing of complex therapeutic proteins.The combination of ProBioGen's CHO.RiGHT expression platform and state-of-the-art process development platforms, together with intelligent and innovative product-specific technologies yield biologics with optimized properties.LAVA Therapeutics N.V. is a biotechnology company developing a portfolio of bispecific gamma-delta T cell engagers (gamma-delta bsTCEs) for the treatment of solid tumors and hematologic malignancies based on its proprietary platform.

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