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  3. Jiangsu Recbio Technology Completes First Batch Of Subject Enrollment In Phase I Trial Of Novel Adjuvanted Recombinant Shingles Vaccine Rec610
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  • 15 Feb 2023
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Jiangsu Recbio Technology completes first batch of subject enrollment in phase I trial of novel adjuvanted recombinant shingles vaccine, REC610

Jiangsu Recbio Technology Co., Ltd., an innovative vaccine company driven by self-developed technologies, announced that the Group has recently completed the first batch of subject enrollment for its novel adjuvanted recombinant shingles vaccine, REC610. The study is a randomized, observer-blinded, GSK Shingrix active-controlled phase I clinical trial to evaluate the safety and immunogenicity of REC610 in healthy adult subjects aged 40 and above. According to research data on shingles vaccines that have been marketed around the world, the novel adjuvanted vaccine can provide stronger cellular immunity and protective efficacy as compared to live attenuated vaccines. REC610 is equipped with a novel adjuvant BFA01 independently developed by the company, which can promote the production of high levels of VZV glycoprotein E (gE)-specific CD4+ T cells and antibody. Preclinical studies have shown that REC610 has favourable immunogenicity and can induce high levels of gE-specific CD4+ T cell responses and IgG antibody, and its immune response is non-inferior to the controlled vaccine Shingrix. Founded in 2012, Jiangsu Recbio Technology Co., Ltd. is an innovative vaccine company driven by self-developed technologies. The company dedicated to the R&D, production and commercialization of innovative vaccines, leveraging our core technology platforms (novel adjuvant, protein engineering, immunological evaluation)

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