Jacobio Pharma Receives IND Approval for PARP7 Inhibitor JAB-26766 in China
Jacobio Pharma (1167.HK) has received IND (Investigational New Drug) approval of its self-developed drug JAB-26766 (PARP7 inhibitor) from the Center for Drug Evaluation (CDE) of China. Jacobio plans to initiate a Phase I/IIa advanced solid tumors clinical trial in the China.
PARP7 inhibitors target I/O (immuno-oncology) signaling pathway and can be used to treat various solid tumors such as squamous NSCLC, and HNSCC. Studies show that, PARP7 inhibitors have the potential to directly inhibit tumor growth and enhance the anti-tumor immune response. JAB-26766 is an orally administered small-molecule with significant antitumor activity against a variety of tumor models in mice.
PARP7 is located downstream of STING signaling pathway, and JAB-26766 has potential to combine with Jacobio
Let’s apply Data-Driven Pricing to Your APIs
Sick and tired of always wondering if you are being asked to pay the right price for your APIs? This empowers you with the answers you need to make the right decisions in the Global API market.
Chemxpert Database is one of the biggest and most comprehensive directories of pharma and chemicals, manufacturers, suppliers and information. Provided with current information on prices, demand and transactions, it gives you instant feedback on whether you are buying what is right and at the right time.
Start using market intelligence today and allow yourself to be in control in the API market.
Check it out today and make more informed sourcing decisions!
Learn More!