1. What is the Chemxpert database?

Chemxpert database is a techno-commercial information platform developed and operated by Lifescience Intellipedia Pvt. Ltd. Our data provides valuable insights regarding sourcing, marketing, development, and regulatory functions for the entire Lifescience industry. The different industries covered by our data encompass APIs, FDFs, pharma intermediates, paints, dyes, polymers, biotechnology, biochemical, food additives, nutraceuticals, etc.

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You can gain access to the Chemxpert database after subscribing to it by visiting this link: - https://chemxpert.com/pricing

3. How many countries' data is available on your portal?

The Chemxpert database covers more than 200 countries. We are working in the direction of expanding our data coverage in more countries.

4. What are the different sources you use for obtaining information?

The different sources we use for data collection are as follows: - • Primary researc • DMF, ANDA, & CEP list • Conferences, Exhibitions, & Tradeshow • Company annual reports • DMF, ANDA, & CEP list • Subject matter experts & KOL survey. Apart from these, our other valuable sources include application-wise manufacturers list, subscribed and non-subscribed databases, corporate partners, US FDA Orange book, publicly available sources, industry associates, national statistics, regulatory websites, etc. You can gain access to the Chemxpert database after subscribing to it by visiting this link: -https://chemxpert.com/sources

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Your Chemxpert account will be activated instantly if the payment is made through our website. If you choose to use RTGS, NEFT, or IMPS systems for payment, your account will be activated within 24 hours.

11 Sep 2020
Admin
News Article

Gannex Galmed Enter Into Research Agreement For Nash Treatment

China-Based Gannex Pharma Co. Ltd., A Wholly-Owned Company Of Ascletis Pharma Inc. And Galmed Pharmaceuticals Ltd. In Israel Have Recently Announced That They Have Entered Into A Research Agreement Aiming At Combination Therapy Of Asc41 (Thr-Beta Agonist) And Aramchol (Scd 1 Inhibitor) For The Treatment Of Non-Alcoholic Steatohepatitis (Nash).Asc41 Is An Oral Thyroid Hormone Receptor Beta (Thr-Beta) Agonist Which Recently Received Ind Approval From China'S National Medical Products Administration (Nmpa) To Conduct Clinical Trials For Nash Indication. Topline Data Of Phase I Safety, Pk And Preliminary Efficacy (Ldl-C) In Healthy Volunteers With Ldl-C ≫ 110 Mg/Dl Is Expected To Be Available By The End Of 2020.Asc41'S Active Moiety Selectively Activates Thr-Beta Resulting In The Improvement Of Steatosis/Lipotoxicity, Inflammation, Ballooning, Fibrosis In Both Direct And Indirect Manner. In Two Nash Animal Models, Asc41 Demonstrated The Same Improvement In Liver Steatosis, Inflammation And Fibrosis At 1/10 Dose Of Resmetirom (Mgl-3196), Another Thr-Beta Agonist Currently In Phase Iii Clinical Trial.In Hepatocytes, The Reduction Of Scd 1 Results In Elevation Of Ampk, Fa Oxidation And Glutathione Ratio. In Hsc'S Inhibition Of Scd 1 Results In Specific Up Regulation Of Ppar Y Which Blocks Collagen Production. In Phase Ii Clinical Trials For Nash, Aramchol Significantly Reduced Liver Fat, Improved Liver Histology I.E., Ballooning And Fibrosis, Hepatic Biochemistry And Glycemic Parameters With Favorable Safety And Tolerability Profile.Aramchol Is Currently In Phase Iii Registrational Study For Nash And Fibrosis (Armor) And Has Been Granted Fast Track Designation Status By The Fda For The Treatment Of Nash.

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