Fujifilm Corporation Announces The Initiation Of A Us Phase Ii Clinical Trial To Evaluate The Safety And Efficacy Of Its Influenza Antiviral Drug Avigan Tablet ( Favipiravir) For Patients With Covid-19, A Respiratory Infection Caused By The Novel Sars-Cov-2 Coronavirus.Avigan, Approved In Japan For Manufacture And Sale As An Influenza Antiviral Drug, Selectively Inhibits Rna Polymerase Necessary For Influenza Virus Replication. Due To This Mechanism Of Action, It Is Expected That Avigan May Potentially Have An Antiviral Effect On The New Coronavirus, Because Like Influenza Viruses, Coronaviruses Are Single-Stranded Rna Viruses That Also Depend On Viral Rna Polymerase. On March 31St, Fujifilm Announced The Start Of A Phase Iii Clinical Trial Of Avigan For Covid-19 Patients In Japan.The Clinical Trial In The Us Will Enroll Approximately 50 Patients With Covid-19, In Collaboration With Brigham And Women'S Hospital, Massachusetts General Hospital, And The University Of Massachusetts Medical School.Fujifilm Will Continue To Work To Establish A Treatment Method For Covid-19 Patients Through Conducting Clinical Trials, And To Contribute To Ending The Spread Of This Global Pandemic As Soon As Possible By Increasing The Production Of Avigan In Collaboration With Strategic Partners.Avigan Tablet Was Approved For Manufacture And Sale In Japan In 2014 As An Influenza Antiviral Drug. The Drug Is To Be Considered For Use Only When There Is An Outbreak Of Novel Or Re-Emerging Influenza Virus Infections In Which Other Influenza Antiviral Drugs Are Either Not Effective Or Insufficiently Effective, And The Japanese Government Decides To Use The Drug As A Countermeasure Against Such Influenza Viruses.The Drug Is To Be Supplied Only At The Discretion Of Japan'S Health, Labor And Welfare Ministry. It Is Therefore Only Manufactured And Distributed Upon Request By The Japanese Government. As Such Avigan Has Never Been Generally Distributed In The Market And Is Not Available At Hospitals And Pharmacies In Japan. Avigan Is Not Approved For Distribution In The Us Or Any Overseas Countries.
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