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Chemxpert database is a techno-commercial information platform developed and operated by Lifescience Intellipedia Pvt. Ltd. Our data provides valuable insights regarding sourcing, marketing, development, and regulatory functions for the entire Lifescience industry. The different industries covered by our data encompass APIs, FDFs, pharma intermediates, paints, dyes, polymers, biotechnology, biochemical, food additives, nutraceuticals, etc.

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02 Sep 2022
Admin
News Article

Daiichi Sankyo begins phase 3 trial of mRNA Covid-19 vaccine, DS-5670) in unvaccinated individuals in Japan

Daiichi Sankyo announced that it has initiated a phase 3 trial of DS-5670, an mRNA vaccine against the novel coronavirus infectious disease (Covid-19), in healthy unvaccinated adults. The trial is an active-controlled, trial to investigate the non-inferiority of DS-5670 to an already-approved mRNA vaccine (Comirnaty) in terms of immunogenicity and seroconversion rate in 322 healthy adults in Japan who have not yet received a Covid-19 vaccine or been infected with the novel coronavirus. As a Japanese pharmaceutical company with specialty in developing vaccines, Daiichi Sankyo is proceeding with the development of DS-5670 and will continue consultation with regulatory authorities to deliver a domestically produced mRNA vaccine to people in Japan as soon as possible. DS-5670 is an mRNA vaccine against Covid-19 using a cationic lipid discovered by Daiichi Sankyo, designed to produce antibodies against the receptor binding domain (RBD) of the spike protein of the novel coronavirus, and thus expected to have desirable efficacy and safety. In addition, DS-5670 in animal models induced neutralizing activities against the omicron variant to a certain extent following the initial vaccination. The clinical development of DS-5670 is being conducted through

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