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  3. Bd And University Of Pennsylvania Partner To Advance Deep Human Immune Profiling
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  • 23 Dec 2025
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  • News Article

BD and University of Pennsylvania Partner to Advance Deep Human Immune Profiling

BD (Becton, Dickinson and Company) has entered a strategic research collaboration with the Institute for Immunology and Immune Health (I3H) at the University of Pennsylvania.
The goal is clear: push the boundaries of deep human immune profiling and accelerate immune-mediated therapy development.

This partnership brings together cutting-edge technology and academic expertise to decode how the human immune system behaves at a single-cell level.

What the Collaboration Focuses On?

At the core of the collaboration is the development of a high-parameter flow cytometry panel. This panel is designed to capture critical immune pathways directly from whole blood.

Key capabilities include:

  • Measurement of phosphorylation markers, revealing how cells respond to disease or drug exposure
  • High-resolution insights into single-cell functional behavior
  • Improved understanding of immune dysregulation in complex diseases

The 1,000-Patient Immune Profiling Study

The new panel will support a large-scale 1,000-patient immune profiling study. The study is being conducted with the Penn Colton Center for Autoimmunity.

Important details:

  • Study expected to begin this summer
  • Focused on autoimmune and immune-mediated conditions
  • Results intended for publication in a peer-reviewed journal

This scale of profiling was once considered impractical. That has changed.

Technology Powering the Research

The collaboration will leverage BD’s advanced single-cell ecosystem, including:

  • BD FACSDiscover A8 Cell Analyzer for spectral and real-time cell imaging
  • BD Rhapsody System for single-cell analysis
  • BD reagents, software, and informatics platforms

BD teams will manage instrumentation, reagents, and spectral algorithms. I3H will lead scientific direction and clinical interpretation.

Why This Matters for Immunology Research?

According to Dr. E. John Wherry of the University of Pennsylvania, this project highlights the power of industry–academic collaboration. The aim is to extract deeper, more actionable insights from immune cells.

High-parameter single-cell studies are now becoming essential, not experimental. They enable precision medicine approaches that were previously out of reach.

A Shared Vision for Translational Impact

The collaboration reflects a common objective:.

translate complex immune data into meaningful clinical insights.

BD’s latest platforms, including the BD Horizon Chroma solution, are helping make high-parameter studies more accessible and scalable.

As BD Biosciences president Steve Conly noted, these tools provide the missing link between discovery science and real-world clinical application.

The Bigger Picture

BD continues to position itself at the intersection of:

  • Advanced diagnostics
  • Single-cell technologies
  • Translational research

By partnering with institutions like I3H, BD is helping transform immune profiling from a research challenge into a clinical advantage.

This collaboration could reshape how immune-mediated diseases are studied, diagnosed, and treated worldwide.

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