Amyris, Inc., a leading synthetic biotechnology company, announced that it has signed an exclusive license agreement with British specialty chemicals company Croda International Plc, (Croda) for the supply of sustainable squalene. Amyris' squalene is a biofermentation-based adjuvant developed using Amyris' unique Lab-to-Market technology platform. Squalene, used in adjuvants to boost immune responses, is commonly derived from shark liver. Amyris' sugarcane-derived, sustainable squalene is molecularly identical to the traditional shark source, offering a higher purity and a more predictable cost profile compared to sourcing directly from sharks. Under the terms of the agreement, Amyris will manufacture and supply squalene to Croda and Croda will license squalene technology from Amyris to market, distribute, and sell squalene as an excipient, or as an ingredient in formulated products for use in human and veterinary vaccines, drug delivery systems, or nucleic acid delivery systems. Croda will also leverage its experience with good manufacturing practices for the pharmaceutical industry and accelerate commercialization of the final packaged squalene products. In addition to an upfront payment of $4 million and a future
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